منابع مشابه
Efficacy of Phonophoresis Therapy in Freund’s Adjuvant Induced Arthritic Rats
The effect of phonophoresis was assessed using Frund’s complete adjuvant (FCA) induced arthritis in rats. Plumbago zeylanica (0.5g) root extract was prepared to obtain 0.5% gel. The animals were divided into four groups. Group I serves as normal. Group II to IV served as arthritis animals induced by FCA. Group III and IV treated with ultrasound and phonophoresis (Application of ultrasound along...
متن کاملAnti-arthritic Effect of 1'-acetoxychavicol Acetate in Complete Freunds Adjuvant-induced Arthritis in Rats
1'-Acetoxychavicol acetate (ACA) is a phenylpropanoid present in Alpinia galanga (L) Willd syn. Languas galanga. The objective of this study was to isolate 1'-Acetoxychavicol acetate (ACA) from acetone extract of Alpinia galanga (AEAG) and evaluate anti-arthritic activity of 1'-Acetoxychavicol acetate (ACA) and acetone extract of Alpinia galanga (AEAG) on complete Freund’s Adjuvant-induced arth...
متن کاملAllodynia and hyperalgesia in adjuvant-induced arthritic rats: time course of progression and efficacy of analgesics.
The complete Freund's adjuvant (CFA)-induced arthritic rat model has extensively served as a laboratory model in the study of arthritic pain. However, the time courses of allodynia and hyperalgesia and the efficacies of different analgesics have not fully been analyzed in this model. Mechanical allodynia, thermal and joint hyperalgesia, and other disease development parameters (body weight, mob...
متن کاملEffect of Flueggea Leucopyrus Leaf on Inflammatory Markers in Freund’s Complete Adjuvant Induced Arthritic Rats
Many plant-derived compounds have been used as drugs, either in their original or semi-synthetic form. Plant secondary metabolites can also serve as drug precursors, drug prototypes and pharmacological probes. Due to these side-effects, there is need for the search of newer drugs with less or no side-effects. In the present study to investigate the anti-arthritic activity of Flueggea leucopyrus...
متن کاملStereoselective Pharmacokinetics and Chiral Inversion of Ibuprofen in Adjuvant-induced Arthritic Rats.
2-Arylpropionic acid (2-APA) nonsteroidal anti-inflammatory drugs are commonly used in racemic mixtures (rac) for clinical use. 2-APA undergoes unidirectional chiral inversion of the in vivo inactive R-enantiomer to the active S-enantiomer. Inflammation causes the reduction of metabolic activities of drug-metabolizing enzymes such as cytochrome P450 (P450) and UDP-glucuronosyltransferase. Howev...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1975
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)65555-1